MOSCOW — NATO and Kazakhstan completed an agreement Wednesday that will permit NATO allies to ship cargo through Kazakh territory to Afghanistan, providing an important alternative to vulnerable routes elsewhere.

Kazakhstan was the final holdout in the so-called northern supply line, which will allow cargo to pass overland from Europe to NATO troops in Afghanistan. Russia, Ukraine and Uzbekistan have signed similar agreements.

“This allows supplies for our forces to start moving from Europe to Afghanistan, beginning in the coming days, complementing the very important transit route through Pakistan,” NATO’s secretary general, Anders Fogh Rasmussen, said in a statement in Brussels.

The American-led NATO coalition has been seeking to reduce its reliance on supply routes through the Khyber Pass in Pakistan, where attacks by the Taliban have been frequent.

The accord with Kazakhstan will allow NATO forces to ship only nonlethal cargo by rail through the country’s territory. The cargo will then pass through Uzbekistan into Afghanistan, where the coalition is fighting a growing Taliban insurgency.

The agreement comes as NATO allies prepare to meet Thursday with representatives from Afghanistan and its neighbors in London. The conference, hosted by Prime Minister Gordon Brown of Britain and President Hamid Karzai of Afghanistan, will seek to map out strategies for continued international involvement in the war in Afghanistan.

NATO and the United States have been pushing Central Asian countries near Afghanistan to become more involved in the war effort. Last year, the Obama administration persuaded Kazakhstan’s neighbor, Kyrgyzstan, to reverse a decision to close a United States military base that is an important transit hub and refueling stop for troops en route to Afghanistan.

The alliance has also been working with Russia to open up more supply routes. The United States signed an agreement with Russia last summer to allow flights of troops and weapons through Russian airspace to Afghanistan, though bureaucratic wrangling has so far prevented all but a few shipments.

Russian and NATO military officials met on Tuesday in Brussels to further discuss Russian involvement in Afghanistan, among other issues. It was the first formal meeting between military officials from both sides since diplomatic relations broke down after Russia’s war with Georgia in August 2008.

In Washington, the White House welcomed the agreement, calling it “another signal of the commitment of the government of Kazakhstan to support” the international effort in Afghanistan.

The separate American agreement with Russia permitting overflights of soldiers and weapons has had a slow start but is beginning to ramp up, American officials said.

Six months after President Obama and President Dimitri A. Medvedev sealed the agreement, an administration official said 12 flights have passed through Russian airspace and eight are planned in coming days. The Russians have cleared all flights except one, a chartered commercial carrier with hazardous material on board, the official said.

Peter Baker contributed reporting from Washington.

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